PALMA FLORES, CARLOS

Dr. Carlos Palma-Flores holds a PhD in Biomedical Sciences from the National Autonomous University of Mexico (UNAM). During his PhD he investigated the cellular and molecular mechanisms of muscule contraction. At the postdoctoral level, Dr. Palma employed unbiased high-throughput Genomic and Proteomic technologies to study the contribution of microRNAs to Breast Cancer development at the Autonomous University of Mexico. He currently works as Professor-Investigator in the field of Functional Genomics of skeletal muscle regeneration and microRNA biology at Secretaría de Ciencia, Humanidades, Tecnología e Innovación (SECIHTI) and UACM/Instituto Nacional de Cancerología in Mexico City. He belongs to the SECIHTI-National System of Investigators –SNI level I.

One focus of his laboratory is to identify molecules of different origin that increase the fusion, differentiation and growth process of undifferentiated myoblasts during muscle regeneration. Through genomic and proteomic strategies used in cell and animal models, the group of Dr Palma´ s seeks to identify differentially modulated microRNAs under the influence of nutraceuticals that improve muscle maintenance and function in conditions such as sarcopenia and muscular dystrophy. Current research interests include nuclear microRNA-mediated regulation, chromatin-associated transcriptional control, and the use of bioactive compounds such as (–)-epicatechin to preserve muscle function and plasticity