SIXTO LOPEZ, YUDIBETH
CIENCIAS DE LA VIDA · Nivel 1
Desde 2024 es postdoctoral fellow en Universidad de Granada
Translational medicinal chemist with expertise in drug discovery, computational modelling and the design of innovative therapeutic strategies for rare and...
Translational medicinal chemist with expertise in drug discovery, computational modelling and the design of innovative therapeutic strategies for rare and metabolic diseases. My research integrates medicinal chemistry, molecular modelling and experimental validation to identify and optimize novel therapeutic candidates with translational potential.
My scientific career has evolved from epigenetic drug discovery and HDAC inhibitor development towards the exploration of multifunctional therapeutic approaches, including dual-target modulation and targeted protein degradation. I have contributed to international collaborative projects resulting in peer-reviewed publications, patented inventions and competitive research funding.
My current research focuses on developing multifunctional therapeutic strategies, including dual enzyme inhibition and targeted protein degradation, integrating computational modelling, chemical synthesis and experimental validation.
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| Nombre | YUDIBETH SIXTO LOPEZ |
|---|---|
| Área | BIOLOGÍA Y QUÍMICA |
| Campo | CIENCIAS DE LA VIDA |
| Disciplina | QUÍMICA FARMACÉUTICA |
| Especialidad | DISEÑO, SINTESIS Y ESTUDIO DE NUEVOS FARMACOS |
| CVU | 419018 |
| Institución |
SIN INSTITUCIÓN
|
|---|---|
| Dependencia | NO APLICA |
| Entidad | NO APLICA |
| Nivel | 1 |
| Vigencia | Inicio: 01/01/2024 |
| Fin: 31/12/2028 |
Evolución en el SNII
- Nivel I: 2024–2026
Últimas publicaciones Scopus
- 2026
- Targeting Oxalate Production by Combining Enzyme Inhibition and Proteolysis Activation: A Novel Therapeutic Approach for Primary Hyperoxaluria Type 1 Journal of Medicinal Chemistry · Vol. 69 Article
- 2025
- Molecular dynamics, docking and quantum calculations reveal conformational changes influenced by CYP271A amino acid mutations related to cerebrotendinous xanthomatosis Scientific Reports · Vol. 15 Article
- Synthesis, Spectroscopic Characterization, Drug-Likeness, and Antibacterial Activity of a Novel Triazole Derivative Chemistryselect · Vol. 10 Article
- 2024
- Solvation effects, structural, vibrational analysis, chemical reactivity, nanocages, ELF, LOL, docking and MD simulation on Sitagliptin Chemical Physics Impact · Vol. 8 Article
- Synthesis, Solvent effects, Chemical reactivity, Molecular Docking and Molecular Dynamic Studies of Triazole derivative Journal of Molecular Structure · Vol. 1303 Article

